BDBM50605471 CHEMBL5181620

SMILES COc1ncc2cc3cnccc3c([N+]([O-])=O)c2n1

InChI Key InChIKey=WPPGBVWZGMDXKF-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50605471   

TargetSerine/threonine-protein kinase haspin(Human)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605471(CHEMBL5181620)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human Haspin (470 to 798 residues) expressed in bacterial expression system using ARTKQTARKSTGGKAPRKQLA as substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605471(CHEMBL5181620)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human Haspin kinase domain (470 to 798 residues) expressed in bacteria using histone H3 (1 to 21) peptide as substrate incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605471(CHEMBL5181620)
Affinity DataIC50: 66nMAssay Description:Inhibition of recombinant human HASPIN (470 to 798 residues) expressed in bacterial expression system in presence of ATP by kinomescan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605471(CHEMBL5181620)
Affinity DataIC50: 66nMAssay Description:Inhibition of recombinant human haspin (470 to 798 residues) expressed in bacteria using ARTKQTARKSTGGKAPRKQLA as substrate incubated for 30 mins in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase PLK3(Human)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605471(CHEMBL5181620)
Affinity DataIC50: 117nMAssay Description:Inhibition of human recombinant PLK3 in presence of ATP by kinomescan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase PLK2(Human)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605471(CHEMBL5181620)
Affinity DataIC50: 125nMAssay Description:Inhibition of human PLK2 in presence of ATP by kinomescan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605471(CHEMBL5181620)
Affinity DataIC50: 294nMAssay Description:Inhibition of human PLK1 in presence of ATP by kinomescan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Mouse)
Universite Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605471(CHEMBL5181620)
Affinity DataIC50: 445nMAssay Description:Inhibition of recombinant mouse CLK1 expressed in bacteria using GRSRSRSRSRSR as substrate incubated for 30 mins in presence of ATP by ADP-Glo kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Mouse)
Universite Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605471(CHEMBL5181620)
Affinity DataIC50: 445nMAssay Description:Inhibition of recombinant mouse CLK1 expressed in bacteria using GRSRSRSRSRSR as substrate in presence of ATP measured after 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetDeath-associated protein kinase 3(Human)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605471(CHEMBL5181620)
Affinity DataIC50: 578nMAssay Description:Inhibition of human DAPK3 in presence of ATP by kinomescan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Rat)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605471(CHEMBL5181620)
Affinity DataIC50: 917nMAssay Description:Inhibition of recombinant rat DYRK1A (1 to 499 residues ) expressed in bacterial expression system using KKISGRLSPIMTEQ as substrate measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Rat)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605471(CHEMBL5181620)
Affinity DataIC50: 917nMAssay Description:Inhibition of recombinant rat DYRK1A kinase domain (1 to 499 residues) expressed in bacteria using KKISGRLSPIMTEQ as substrate incubated for 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed