BDBM50605518 CHEMBL5179461

SMILES CN1CCN(c2ncc(NC(=O)c3cc(C(=O)c4c(Cl)ccc(Cl)c4F)c[nH]3)cn2)CC1

InChI Key InChIKey=SURDAOBSMMRZNB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50605518   

TargetMitogen-activated protein kinase 7(Human)
Newcastle University Centre For Cancer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50605518BDBM50605518(CHEMBL5179461)
Affinity DataIC50: 37nMAssay Description:Inhibition of ERK5 (unknown origin) using K-5FAM-LVEPLTPSGEAPNQ-COOH as substrate incubated for 2 hrs in presence of ATP by IMAP-FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Newcastle University Centre For Cancer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50605518BDBM50605518(CHEMBL5179461)
Affinity DataIC50: 2.63E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed