BDBM50605902 CHEMBL5199140

SMILES CCC(=O)N1CCc2nc(OCc3c(C)nnn3-c3ccc(F)cc3)ccc2C1

InChI Key InChIKey=TWPMNPAALDJMPK-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50605902   

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50605902(CHEMBL5199140 | US12370182, Example 24)
Affinity DataKi:  46nMAssay Description:Displacement of [3H]Ro151788 from human recombinant alpha5beta3gamma2 GABAA receptor stably expressed in HEK293 cell membrane assessed as inhibition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandPNGBDBM50605902(CHEMBL5199140 | US12370182, Example 24)
Affinity DataKi:  46nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampulle of membrane homogenate was thawed an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2025
Entry Details
US Patent