BDBM50605904 CHEMBL5179688

SMILES CC(=O)N1Cc2ccc(OCc3c(C)nnn3-c3ccc(F)cc3)nc2C1

InChI Key InChIKey=IGANKKXNZYWZFN-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50605904   

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandPNGBDBM50605904(CHEMBL5179688 | US12370182, Example 45)
Affinity DataKi:  3.20nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampulle of membrane homogenate was thawed an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2025
Entry Details
US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50605904(CHEMBL5179688 | US12370182, Example 45)
Affinity DataKi:  3.20nMAssay Description:Displacement of [3H]Ro151788 from human recombinant alpha5beta3gamma2 GABAA receptor stably expressed in HEK293 cell membrane assessed as inhibition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandPNGBDBM50605904(CHEMBL5179688 | US12370182, Example 45)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of hERG expressed in CHO cells stably at -80 mV holding potential by automated patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed