BDBM50606592 CHEMBL5219838

SMILES Nc1cc(Br)cc2[nH]ncc12

InChI Key InChIKey=JORDVWJEXMDSBI-UHFFFAOYSA-N

Data  2 KI  4 IC50

PDB links: 1 PDB ID matches this monomer.

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50606592   

TargetTryptophan 2,3-dioxygenase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50606592(CHEMBL5219838)
Affinity DataKi:  280nMAssay Description:Binding affinity to human TDO assessed as inhibition constant by Cornhish-Bowden methodMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50606592(CHEMBL5219838)
Affinity DataKi:  4.48E+3nMAssay Description:Binding affinity to human IDO1 assessed as inhibition constant by Cornhish-Bowden methodMore data for this Ligand-Target Pair
TargetTryptophan 2,3-dioxygenase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50606592(CHEMBL5219838)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of human TDO (19 to 388 aa) expressed in Escherichia coli Transetta (DE3) by nanodrop 2000c spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50606592(CHEMBL5219838)
Affinity DataIC50:  8.49E+3nMAssay Description:Inhibition of human IDO1 by Cornhish-Bowden methodMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50606592(CHEMBL5219838)
Affinity DataIC50:  9.54E+3nMAssay Description:Inhibition of human IDO1 (12 to 403 aa) expressed in Escherichia coli Transetta (DE3) by nanodrop 2000c spectrophotometric analysisMore data for this Ligand-Target Pair
TargetTryptophan 2,3-dioxygenase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50606592(CHEMBL5219838)
Affinity DataIC50:  1.39E+3nMAssay Description:Inhibition of human TDO by Cornhish-Bowden methodMore data for this Ligand-Target Pair
In DepthDetails PubMed