BDBM50606749 CHEMBL5220667

SMILES Cc1cc(C)c(C(=O)N2CCN(CC2)c2cccnc2S(N)(=O)=O)c(C)c1NC1CCN(CC1)c1ccccc1C#N

InChI Key InChIKey=BMXAXHINKBUJQZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50606749   

TargetTarget of rapamycin complex subunit LST8(Human)
University of Hradec Kralove

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50606749BDBM50606749(CHEMBL5220667)
Affinity DataIC50: 10nMAssay Description:Inhibition of mTORC1 in human MCF7 cells assessed as measuring phosphorylated S6K1 incubated for 2 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
University of Hradec Kralove

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50606749BDBM50606749(CHEMBL5220667)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mTORC2 in human MCF7 cells assessed as measuring phosphorylated AKT incubated for 2 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed