BDBM50608558 CHEMBL5284956

SMILES COc1ccccc1NC(=O)N[C@H](C(=O)Nc1ccc(cc1)C(=O)NO)c1ccccc1

InChI Key InChIKey=NQRJFGWIXSYDRE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50608558   

TargetHistone deacetylase 1(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50608558(CHEMBL5284956)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of human recombinant HDAC1 using fluorogenic HDAC substrate measured after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50608558(CHEMBL5284956)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of human HDAC3 using fluorogenic as substrate measured after 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50608558(CHEMBL5284956)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of human recombinant HDAC3 using fluorogenic HDAC substrate measured after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50608558(CHEMBL5284956)
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant HDAC2 using fluorogenic HDAC substrate measured after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50608558(CHEMBL5284956)
Affinity DataIC50: 294nMAssay Description:Inhibition of human recombinant HDAC6 using fluorogenic HDAC substrate measured after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed