BDBM50608563 CHEMBL5273740

SMILES ONC(=O)c1ccc(NC(=O)[C@@H](NC(=O)c2cccc(Br)c2)c2ccccc2)cc1

InChI Key InChIKey=GKDSLRGHAAFGPK-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50608563   

TargetHistone deacetylase 3(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50608563(CHEMBL5273740)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of human HDAC3 using fluorogenic as substrate measured after 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50608563(CHEMBL5273740)
Affinity DataIC50: 12nMAssay Description:Inhibition of human HDAC1 using fluorogenic as substrate measured after 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50608563(CHEMBL5273740)
Affinity DataIC50: 14nMAssay Description:Inhibition of human HDAC using human HeLa cell nuclear extract measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50608563(CHEMBL5273740)
Affinity DataIC50: 89nMAssay Description:Inhibition of human HDAC2 using fluorogenic as substrate measured after 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50608563(CHEMBL5273740)
Affinity DataIC50: 196nMAssay Description:Inhibition of human HDAC6 using fluorogenic as substrate measured after 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed