BDBM50609047 CHEMBL5273113

SMILES OC(=O)c1cnc(N2C(=O)CCc3cc(OCc4c(onc4-c4c(Cl)cccc4Cl)C4CC4)ccc23)c(Cl)c1

InChI Key InChIKey=CFPYOIGXQRCSBG-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50609047   

TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50609047(CHEMBL5273113 | US12215098, Formula (I))
Affinity DataEC50:  13nMAssay Description:Agonist activity at human GST-tagged FXR incubated for 1 hrs by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50609047(CHEMBL5273113 | US12215098, Formula (I))
Affinity DataEC50:  13.8nMAssay Description:Purpose of the Assay:Activation of FXR binding reaction by the compound was detected by the amplified luminescent proximity homogeneous assay (alphas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2025
Entry Details
US Patent