BDBM50609271 CHEMBL5290530

SMILES Cc1cnc2n(CCN3CCC(F)(F)CC3)cc(Nc3cnccc3C(O)=O)c2c1

InChI Key InChIKey=KDYQCOVJKZYFKX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50609271   

TargetLysine-specific demethylase 5B(Human)
Ningbo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50609271BDBM50609271(CHEMBL5290530)
Affinity DataIC50: 800nMAssay Description:Inhibition of N-terminal his6-tagged human KDM5B (1 to 769 residues) expressed in sf9 insect cells incubated for 20 mins by Alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetLysine-specific demethylase 5A(Human)
Ningbo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50609271BDBM50609271(CHEMBL5290530)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of N-terminal his6-tagged human KDM5A (1 to 797 residues) expressed in sf9 insect cells incubated for 20 mins by Alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetLysine-specific demethylase 4C(Human)
Ningbo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50609271BDBM50609271(CHEMBL5290530)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of KDM4C (unknown origin) incubated for 20 mins by Alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed