BDBM50610308 CHEMBL5277445

SMILES CS(=O)(=O)N1CCN(Cc2ccc(s2)-c2nc(nc(n2)-c2ccc(NC(=O)Nc3ccncc3)cc2)N2CCOCC2)CC1

InChI Key InChIKey=PVCHFDQWRQFBTJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50610308   

TargetSerine/threonine-protein kinase mTOR(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50610308(CHEMBL5277445)
Affinity DataIC50: 12nMAssay Description:Inhibition of mTOR (unknown origin) by kinase-glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50610308(CHEMBL5277445)
Affinity DataIC50: 177nMAssay Description:Inhibition of PI3Kalpha (unknown origin) by kinase-glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed