BDBM50610577 CHEMBL5283368

SMILES COc1ccc(cc1)C(N1CCN(C)CC1)c1c(-c2ccccc2)n(O)c2ccccc12

InChI Key InChIKey=BBAJRFXAJHAPJE-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50610577   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50610577(CHEMBL5283368)
Affinity DataKi:  400nMAssay Description:Inhibition of BFL-1 (unknown origin)/Bim BH3 peptide (unknown origin) interaction by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50610577(CHEMBL5283368)
Affinity DataKi:  400nMAssay Description:Inhibition of Bfl-1/Bim (unknown origin) assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetBcl-2-related protein A1(Human)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50610577(CHEMBL5283368)
Affinity DataIC50: 800nMAssay Description:Inhibition of Bfl-1 (unknown origin) incubated for 30 min by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50610577(CHEMBL5283368)
Affinity DataIC50: 800nMAssay Description:Inhibition of Bfl-1/Bim (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50610577(CHEMBL5283368)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Bfl-1/Bim (unknown origin) incubated for 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetBcl-2-related protein A1(Human)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50610577(CHEMBL5283368)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of GST-tagged Bfl-1 (unknown origin) incubated for 60 min by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed