BDBM50611356 CHEMBL5268867

SMILES Nc1ncnc2n(nc(-c3cnc4[nH]ccc4c3)c12)[C@@H]1CCCN(C1)C(=O)\C=C(\C#N)C1CC1

InChI Key InChIKey=XUAVCXINBQWRAV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50611356   

TargetEpidermal growth factor receptor(Human)
Yangtze University

Curated by ChEMBL
LigandPNGBDBM50611356(CHEMBL5268867)
Affinity DataIC50: 2nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Yangtze University

Curated by ChEMBL
LigandPNGBDBM50611356(CHEMBL5268867)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Yangtze University

Curated by ChEMBL
LigandPNGBDBM50611356(CHEMBL5268867)
Affinity DataIC50: 13nMAssay Description:Inhibition of wild type EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed