BDBM50611357 CHEMBL5286014

SMILES CN(C)C(=O)Cc1ccc(C(=O)c2nn([C@H]3CCCN(C3)C(=O)C=C)c3ncnc(N)c23)c(C)c1C

InChI Key InChIKey=SCSKESFIGNPXKD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50611357   

TargetReceptor tyrosine-protein kinase erbB-4(Human)
Yangtze University

Curated by ChEMBL
LigandPNGBDBM50611357(CHEMBL5286014)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of HER4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Yangtze University

Curated by ChEMBL
LigandPNGBDBM50611357(CHEMBL5286014)
Affinity DataIC50: 13nMAssay Description:Inhibition of HER2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Yangtze University

Curated by ChEMBL
LigandPNGBDBM50611357(CHEMBL5286014)
Affinity DataIC50: 33nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Yangtze University

Curated by ChEMBL
LigandPNGBDBM50611357(CHEMBL5286014)
Affinity DataIC50: 65nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed