BDBM50611365 CHEMBL5268244

SMILES C[C@@H]1[C@@H](COC(=O)c2ccc(cc2)S(F)(=O)=O)O[C@H]([C@@H]1OCC#C)n1nc(-c2ccc(C)cc2)c2c(N)ncnc12

InChI Key InChIKey=VCIZYTQJDGPPDJ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50611365   

TargetTyrosine-protein kinase Yes(Human)
Yangtze University

Curated by ChEMBL
LigandPNGBDBM50611365(CHEMBL5268244)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of YES (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetFibroblast growth factor receptor 3(Human)
Yangtze University

Curated by ChEMBL
LigandPNGBDBM50611365(CHEMBL5268244)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of FGFR3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Yangtze University

Curated by ChEMBL
LigandPNGBDBM50611365(CHEMBL5268244)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of Src kinase (unknown origin) phosphorylation at Tyr416/419 residues incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase Lyn(Human)
Yangtze University

Curated by ChEMBL
LigandPNGBDBM50611365(CHEMBL5268244)
Affinity DataIC50: 81nMAssay Description:Inhibition of LYN (unknown origin) at 1 uM by kinase-profiling analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Yangtze University

Curated by ChEMBL
LigandPNGBDBM50611365(CHEMBL5268244)
Affinity DataIC50: 182nMAssay Description:Inhibition of Abl (unknown origin) incubated for 1 hr by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Yangtze University

Curated by ChEMBL
LigandPNGBDBM50611365(CHEMBL5268244)
Affinity DataIC50: 475nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed