BDBM50611953 CHEMBL5289716

SMILES CN(CC1(C(=O)NC23CC4CC(C2)CC(C(N)=O)(C4)C3)CC1)S(=O)(=O)c1ccccc1F

InChI Key InChIKey=VEFHANPSESBAGN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50611953   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Hong Kong Baptist University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50611953BDBM50611953(CHEMBL5289716)
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of human 11beta-HSD1 in liver microsome incubated for 24 hrs by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHydroxysteroid 11-beta dehydrogenase 1(Rhesus macaque)
Hong Kong Baptist University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50611953BDBM50611953(CHEMBL5289716)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of monkey 11beta-HSD1 in liver microsome incubated for 24 hrs by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Hong Kong Baptist University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50611953BDBM50611953(CHEMBL5289716)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of mouse 11beta-HSD1 in liver microsome incubated for 24 hrs by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed