BDBM50612136 CHEMBL5271926

SMILES [O-]S(=O)(=O)Oc1ccc(cc1)-c1nc2ccccc2c(=O)n1CCCCCCCCCn1c(nc2ccccc2c1=O)-c1ccc(OS([O-])(=O)=O)cc1

InChI Key InChIKey=UFLRLRHYMXPGKD-UHFFFAOYSA-L

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50612136   

TargetCoagulation factor XI(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50612136(CHEMBL5271926)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of human FXIa using S-2366 as chromogenic substrate preincubated with enzyme for 10 mins followed by substrate addition by spectrophotomet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50612136(CHEMBL5271926)
Affinity DataKd:  1.99E+4nMAssay Description:Binding affinity to active site dansylated human DEGR-FXIa assessed as change in fluorescence intensity by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed