BDBM50612420 CHEMBL5276894

SMILES Fc1ccccc1-c1ccncc1CN1C(ON=C1c1ccco1)c1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=REYRFODIOMJIFC-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50612420   

TargetG-protein coupled bile acid receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50612420(CHEMBL5276894)
Affinity DataEC50:  15nMAssay Description:Agonist activity at human TGR5 expressed in human HEK293 cells measured after 5.5 hrs by steady-glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed