BDBM50612668 CHEMBL5282062

SMILES Nc1ccccc1NC(=O)c1ccc(COc2cccc3C(=O)N(Cc23)C2CCC(=O)NC2=O)cc1

InChI Key InChIKey=RDQXAQYEABCNQH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50612668   

TargetHistone deacetylase 3(Human)
First Affiliated Hospital of Gannan Medical University

Curated by ChEMBL
LigandPNGBDBM50612668(CHEMBL5282062)
Affinity DataIC50: 560nMAssay Description:Inhibition of recombinant human HDAC3 expressed in BTI-TN-5B1-4 insect cells using Ac-Lys-Tyr-Lys(epsilon-acetyl)-AMC as substrate incubated for 24 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
First Affiliated Hospital of Gannan Medical University

Curated by ChEMBL
LigandPNGBDBM50612668(CHEMBL5282062)
Affinity DataIC50: 560nMAssay Description:Inhibition of His6-tagged Gst fused recombinant human HDAC3 using Ac-Lys-Tyr-Lys(epsilon-acetyl)-AMC as substrate expressed in insect Hi-5 cells meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
The Affiliated Hospital of Qingdao University

Curated by ChEMBL
LigandPNGBDBM50612668(CHEMBL5282062)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of His6-tagged Gst fused recombinant human HDAC1 using Ac-Lys-Tyr-Lys(epsilon-acetyl)-AMC as substrate expressed in insect Hi-5 cells meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed