BDBM50613009 CHEMBL5280172

SMILES [H][C@@]12C[C@@]3([H])\C(CN1CC[C@@]14c5ccccc5N(CC)[C@@]21OC[C@@]34C(=O)OC)=C\C

InChI Key

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50613009   

TargetMu-type opioid receptor(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50613009(CHEMBL5280172)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) assessed as inhibition constant incubated for 180 mins by competitive radioligand ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Mouse)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50613009(CHEMBL5280172)
Affinity DataEC50:  240nMAssay Description:Agonist activity at HA-tagged mouse mu opioid receptor expressed in human HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50613009(CHEMBL5280172)
Affinity DataKi:  1.17E+3nMAssay Description:Displacement of [3H]-U69593 from kappa opioid receptor (unknown origin) assessed as inhibition constant incubated for 180 mins by competitive radioli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed