BDBM50613195 CHEMBL5274108

SMILES COc1cc2nc(C)nc(NC(C)c3cc(N)cc(c3)C(F)(F)F)c2cc1C1CCN(CC1)C(C)=O

InChI Key InChIKey=LLNGAMFFBFKOHI-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50613195   

TargetSon of sevenless homolog 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50613195(CHEMBL5274108)
Affinity DataKd:  27nMAssay Description:Binding affinity to GST-tagged human SOS1 (564 to 1049 residues) expressed in Escherichia coli BL21 (DE3) cells assessed as binary complex formation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetSon of sevenless homolog 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50613195(CHEMBL5274108)
Affinity DataKd:  27nMAssay Description:Binding affinity to GST-tagged human SOS1 (564 to 1049 residues) expressed in Escherichia coli BL21 (DE3) cells assessed as ternary complex formation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed