BDBM50613399 CHEMBL5276348

SMILES FC(F)(F)COc1ccncc1NC(=O)c1ccnc(NC(=O)C2CC2)c1

InChI Key InChIKey=XAPPKVUCFSPXNL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50613399   

TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))TBA
LigandPNGBDBM50613399(CHEMBL5276348)
Affinity DataIC50:  260nMAssay Description:Inhibition of GSK-3beta (unknown origin) assessed as decrease in tau phosphorylation by high content cell based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))TBA
LigandPNGBDBM50613399(CHEMBL5276348)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of GST tagged GSK-3beta (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50613399(CHEMBL5276348)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of GST tagged GSK-3alpha (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed