BDBM50614151 CHEMBL5273514

SMILES COc1ccc(cc1)C#Cc1cccc2cc(C(C)Nc3ncnc4[nH]cnc34)n(-c3ccccc3)c(=O)c12

InChI Key InChIKey=GKTONYLGKRMRDV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50614151   

LigandPNGBDBM50614151(CHEMBL5273514)
Affinity DataIC50: 13nMAssay Description:Antagonist activity at PI3Kdelta (unknown origin) using PIP2 as substrate in presence of ATP incubated for 30 to 60 mins by ADP-glo based luminescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
LigandPNGBDBM50614151(CHEMBL5273514)
Affinity DataIC50: 109nMAssay Description:Antagonist activity at PI3Kbeta (unknown origin) using PIP2 as substrate in presence of ATP incubated for 30 to 60 mins by ADP-glo based luminescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
LigandPNGBDBM50614151(CHEMBL5273514)
Affinity DataIC50: 208nMAssay Description:Antagonist activity at PI3Kgamma (unknown origin) using PIP2 as substrate in presence of ATP incubated for 30 to 60 mins by ADP-glo based luminescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed