BDBM50614157 CHEMBL5277217

SMILES [2H]C([2H])(Oc1nc2CN(CCc2c(n1)N1CC2CCC(C1)N2)c1cc(O)ccc1C(F)(F)F)C12CCCN1CCC2

InChI Key InChIKey=HMCHLNGPWJSGGW-FBCWWBABSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50614157   

TargetGTPase KRas(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50614157(CHEMBL5277217)
Affinity DataIC50: 250nMAssay Description:Inhibition of GTP bound KRAS G12D mutant in human GP2d cells assessed as reduction in pERK level incubated for 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed