BDBM50614176 CHEMBL5275918
SMILES COc1cc(NC(=O)c2nn([C@H]3CCN(C3)C(=O)C=C)c3ncnc(N)c23)cc(OC)c1
InChI Key InChIKey=HZLLOAHTNOGYBJ-ZDUSSCGKSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50614176
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of recombinant human EGFR del19/T790M using biotinEEPLYWSFPAKKK-NH2 as substrate incubated for 120 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 670nMAssay Description:Inhibition of human recombinant cytoplasmic domain FGFR2 (8 to 134 residues) incubated for 120 mins by mobility shift assayMore data for this Ligand-Target Pair