BDBM50614318 CHEMBL5278707

SMILES Fc1ccc2CN(Cc2c1)C(=O)Nc1ccc(cc1)-c1n[nH]c(=O)c2CCCCc12

InChI Key InChIKey=LAIYLGVPZPZFRQ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50614318   

TargetRho-associated protein kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50614318(CHEMBL5278707)
Affinity DataKi:  2.40nMAssay Description:Inhibition of ROCK2 (unknown origin) using S6-peptide as substrate in presence of [33P]-ATP by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))TBA
LigandPNGBDBM50614318(CHEMBL5278707)
Affinity DataIC50:  45nMAssay Description:Inhibition of recombinant human C-terminally-His tagged NAMPT incubated for 2 to 3 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed