BDBM50614630 CHEMBL5287596

SMILES CC(C)(C)c1ccc(Cn2cnc3c(NC(=O)c4ccc(cc4)C(O)=O)cccc23)cc1

InChI Key InChIKey=CLIXWGHODIYTCM-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50614630   

TargetBile acid receptor(Human)
Hiroshima International University

Curated by ChEMBL
LigandPNGBDBM50614630(CHEMBL5287596)
Affinity DataEC50:  140nMAssay Description:Partial agonist activity at FXR-LBD-GST (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
Hiroshima International University

Curated by ChEMBL
LigandPNGBDBM50614630(CHEMBL5287596)
Affinity DataEC50:  2.20E+3nMAssay Description:Partial agonist activity at human FXR expressed in Huh-7 cells in presence of CDCA by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed