BDBM50614704 CHEMBL5279540

SMILES Cc1ccc(NC(=O)Nc2cc(cc3[C@H](c4ccccc4)C(Oc23)(C=C)C=C)-c2ccccc2-c2nn[nH]n2)cc1

InChI Key InChIKey=ZHVHMEOMIDRYBQ-LJAQVGFWSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50614704   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50614704(CHEMBL5279540)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of IDO1 (unknown origin) expressed in human HeLa cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50614704(CHEMBL5279540)
Affinity DataIC50: >7.50E+3nMAssay Description:Inhibition of TDO (unknown origin) expressed in HEK cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome P450 2C8(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50614704(CHEMBL5279540)
Affinity DataIC50:  270nMAssay Description:Inhibition of CYP2C8 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50614704(CHEMBL5279540)
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of hERGMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50614704(CHEMBL5279540)
Affinity DataEC50:  7.10E+3nMAssay Description:Transactivation of PXR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed