BDBM50614741 CHEMBL5285029

SMILES CC1=CC(C)=[N+]2C1=C(c1nc(C)cn1[B-]2(F)F)c1ccc(OCCn2cc(CCCCCOc3cc(nc4c(C)c5nc(cc(O)c5cc34)C(O)=O)C(O)=O)nn2)cc1

InChI Key InChIKey=LGKGNSNLRIGZKH-UHFFFAOYSA-N

Data  2 IC50  1 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50614741   

TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50614741(CHEMBL5285029)
Affinity DataIC50: 5.60nMAssay Description:Agonist activity at GPR-35 in human HT-29 cells assessed as desensitization of zaprinast induced DMR response incubated for 1 hr followed by zaprinas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50614741(CHEMBL5285029)
Affinity DataKd:  8.30nMAssay Description:Binding affinity to Nluc-fused human GPR35 expressed in CHO-K1 cells using furimazine as substrate incubated for 30 mins in presence of zaprinast fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50614741(CHEMBL5285029)
Affinity DataEC50:  42nMAssay Description:Agonist activity at GPR-35 in human HT-29 cells by DMR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50614741(CHEMBL5285029)
Affinity DataIC50: 398nMAssay Description:Agonist activity at GPR-35 in human HT-29 cells assessed as desensitization of zaprinast induced DMR response incubated for 1 hr followed by zaprinas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed