BDBM50614879 CHEMBL5274362

SMILES C[C@H]1Nc2nn3c(cnc3cc2C)C(=O)NC2(CC2)COc2ccc(F)cc12

InChI Key InChIKey=YDSXGDDMNFJZBC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50614879   

TargetALK tyrosine kinase receptor(Human)
Shanghai Institute of Pharmaceutical Industry Co.

Curated by ChEMBL
LigandPNGBDBM50614879(CHEMBL5274362)
Affinity DataIC50: 18nMAssay Description:Inhibition of wild type ALK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Shanghai Institute of Pharmaceutical Industry Co.

Curated by ChEMBL
LigandPNGBDBM50614879(CHEMBL5274362)
Affinity DataIC50: 47nMAssay Description:Inhibition of ALK G1202R mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed