BDBM50615021 CHEMBL5273537

SMILES [H][C@]12CN(CCS(C)(=O)=O)[C@]([H])(C[C@H]1c1sc3[nH]c(c(C(C)C)c3c1C)-c1cn3ncnc3c3CCCc13)C2

InChI Key InChIKey=GMLPAPHMKHZBJP-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50615021   

TargetToll-like receptor 8(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615021BDBM50615021(CHEMBL5273537 | US20250049780, Example 40)
Affinity DataEC50:  0.110nMAssay Description:Antagonist activity at human TLR8 expressed in human PBMC cells preincubated for 1 hr followed by GS-986 stimulation measured after 6 hrs by electroc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615021BDBM50615021(CHEMBL5273537 | US20250049780, Example 40)
Affinity DataEC50:  0.270nMAssay Description:Antagonist activity at human TLR7 expressed in human PBMC cells preincubated for 1 hr followed by GS-986 stimulation measured after 6 hrs by electroc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed