BDBM50615023 CHEMBL5266091

SMILES CC(C)c1c([nH]c2sc(C3C[C@@]4(C3)CNCCO4)c(C)c12)-c1cn2ncnc2c2CCCc12

InChI Key InChIKey=ZFTAKZHGZFJNOZ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50615023   

TargetToll-like receptor 7(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615023BDBM50615023(CHEMBL5266091 | US20250049780, Example 26)
Affinity DataEC50:  0.0700nMAssay Description:Antagonist activity at human TLR7 expressed in human PBMC cells preincubated for 1 hr followed by GS-986 stimulation measured after 6 hrs by electroc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetToll-like receptor 8(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615023BDBM50615023(CHEMBL5266091 | US20250049780, Example 26)
Affinity DataEC50:  0.180nMAssay Description:Antagonist activity at human TLR8 expressed in human PBMC cells preincubated for 1 hr followed by GS-986 stimulation measured after 6 hrs by electroc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed