BDBM50615062 CHEMBL5280012

SMILES CN1CCN(CC1)c1ccc(Nc2ncc3c(n2)n([nH]c3=O)-c2cccc(n2)C(C)(C)O)cc1

InChI Key InChIKey=FASYQNVBURRMKN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50615062   

TargetWee1-like protein kinase(Human)
University of Colorado

US Patent
LigandPNGBDBM50615062(CHEMBL5280012 | US12220415, Compound CM-235)
Affinity DataIC50: 152nMAssay Description:A LanthaScreen kinase activity assay was conducted to assess WEE1 kinase inhibitory activity for compounds of this disclosure. LanthaScreen Eu time-r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetWee1-like protein kinase(Human)
University of Colorado

US Patent
LigandPNGBDBM50615062(CHEMBL5280012 | US12220415, Compound CM-235)
Affinity DataIC50: 240nMAssay Description:Inhibition of human full length GST-tagged WEE1 expressed in insect cells incubated for 15 mins followed by ATP addition by ADP Glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Emd Serono

Curated by ChEMBL
LigandPNGBDBM50615062(CHEMBL5280012 | US12220415, Compound CM-235)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human N-terminal His6-tagged recombinant full-length PLK1 expressed in baculovirus infected Sf9 cells incubated for 15 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed