BDBM50615779 CHEMBL5285125

SMILES C[C@H]1CCN1c1ccc2cc(cnc2n1)C(=O)N[C@H]1CC[C@@H](CC1)C(C)(C)O

InChI Key InChIKey=ROWLOFVLOJIUBH-WBAXXEDZSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50615779   

TargetHematopoietic prostaglandin D synthase(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50615779(CHEMBL5285125)
Affinity DataEC50:  14nMAssay Description:Inhibition of H-PGDS in rat RBL cells assessed as reduction in A23187-induced PGD2 production pretreated for 30 mins followed by A23187 addition for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHematopoietic prostaglandin D synthase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50615779(CHEMBL5285125)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed