BDBM50615788 CHEMBL5272443

SMILES O=C(N[C@H]1CC[C@H](N[C@H](CO)C(F)(F)F)CC1)c1cnc2cc(C3CC3)ncc2c1

InChI Key InChIKey=NTMIRLYSNJNTGO-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50615788   

TargetHematopoietic prostaglandin D synthase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615788BDBM50615788(CHEMBL5272443)
Affinity DataIC50: 31nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHematopoietic prostaglandin D synthase(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615788BDBM50615788(CHEMBL5272443)
Affinity DataEC50:  310nMAssay Description:Inhibition of H-PGDS in rat RBL cells assessed as reduction in A23187-induced PGD2 production pretreated for 30 mins followed by A23187 addition for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed