BDBM50616184 CHEMBL5437515

SMILES COc1ccc(cc1)C1(CC(F)(F)C1)C(=O)N1C[C@H](F)C[C@@H]1C(=O)Nc1ccc2[nH]ncc2n1

InChI Key InChIKey=TURGXTFEXLEVEN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50616184   

TargetHistone acetyltransferase p300(Human)
Daiichi Sankyo Co.

Curated by ChEMBL
LigandPNGBDBM50616184(CHEMBL5437515)
Affinity DataIC50: 20nMAssay Description:Inhibition of EP300 in human LK2 cells assessed as reduction in intracellular H3K27 acetylation incubated for 3 hrs by chemiluminescence based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Daiichi Sankyo Co.

Curated by ChEMBL
LigandPNGBDBM50616184(CHEMBL5437515)
Affinity DataIC50: 24nMAssay Description:Inhibition of recombinant human full length EP300 assessed as inhibition of H4 peptide acetylation using biotinylated H4 peptide as substrate in pres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed