BDBM50616398 CHEMBL5427522

SMILES O\N=C(/Nc1ccc(F)c(Br)c1)c1nonc1NCCCCCCNC(=O)c1ccc2nccn2c1

InChI Key InChIKey=CGHBNLCYTYSIJV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50616398   

TargetNicotinamide phosphoribosyltransferase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50616398(CHEMBL5427522)
Affinity DataIC50: 58nMAssay Description:Inhibition of recombinant NAMPT (unknown origin) incubated for 60 mins by SpectraMax microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50616398(CHEMBL5427522)
Affinity DataIC50: 160nMAssay Description:Inhibition of human recombinant IDO1 in human HeLa cells assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50616398(CHEMBL5427522)
Affinity DataIC50: 233nMAssay Description:Inhibition of human recombinant IDO1 assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate preincubated for 30 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed