BDBM50616549 CHEMBL5424664

SMILES NS(=O)(=O)c1ccc(nc1)N1CC[C@H](C1)NC(=S)Nc1ccccc1

InChI Key InChIKey=RURNFMSWOBQBQV-UHFFFAOYSA-N

Data  6 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50616549   

TargetCarbonic anhydrase 7(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50616549(CHEMBL5424664)
Affinity DataKi:  8.5nMAssay Description:Inhibition of human CA7 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetCarbonic anhydrase 9(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50616549(CHEMBL5424664)
Affinity DataKi:  26nMAssay Description:Inhibition of human CA9 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50616549(CHEMBL5424664)
Affinity DataKi:  46nMAssay Description:Inhibition of human CA2 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetCarbonic anhydrase 12(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50616549(CHEMBL5424664)
Affinity DataKi:  59nMAssay Description:Inhibition of human CA12 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetCarbonic anhydrase 1(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50616549(CHEMBL5424664)
Affinity DataKi:  164nMAssay Description:Inhibition of human CA1 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetCarbonic anhydrase 4(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50616549(CHEMBL5424664)
Affinity DataKi:  3.73E+3nMAssay Description:Inhibition of human CA4 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
LigandPNGBDBM50616549(CHEMBL5424664)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human TRPV1 expressed in SH-SY5Y cells measured for 25 mins in presence of capsaicin by fluorescence based microplate reader anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed