BDBM50617041 CHEMBL5403087

SMILES Cc1nc(N[C@H]2CCN(C2)C(=O)Cc2ccc(F)cc2)ccc1-c1nc(n(C)n1)C(F)(F)F

InChI Key InChIKey=FOWFRNKFAURWIW-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50617041   

TargetMelanocortin receptor 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50617041(CHEMBL5403087)
Affinity DataKi:  5.5nMAssay Description:Antagonist activity at human MC4R in CHO cells measured for 24 hrs in presence of alpha-MSHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetMelanocortin receptor 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50617041(CHEMBL5403087)
Affinity DataIC50: 210nMAssay Description:Antagonist activity at human MC4R in CHO cells measured for 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
LigandPNGBDBM50617041(CHEMBL5403087)
Affinity DataIC50: 7.80E+4nMAssay Description:Inhibition of hERG expressed in CHO cells stably at -80 mV holding potential by automated patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed