BDBM50617053 CHEMBL5437282

SMILES COc1cc([C@@H](C)C(=O)N2CC[C@@H](C2)Nc2ccc(-c3nc(n(C)n3)C(F)(F)F)c(C)n2)c(F)cn1

InChI Key InChIKey=ULQWRELSYOPZMD-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50617053   

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM50617053(CHEMBL5437282 | US20250129048, Example 2)
Affinity DataKi:  1.20nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM50617053(CHEMBL5437282 | US20250129048, Example 2)
Affinity DataKi:  1.20nMAssay Description:Antagonist activity at human MC4R in CHO cells measured for 24 hrs in presence of alpha-MSHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed