BDBM50617055 CHEMBL5437236

SMILES COc1cc([C@@H](C)C(=O)N2CC[C@@H](C2)Nc2ccc(-c3n[nH]c(n3)C(F)F)c(C)n2)c(F)cn1

InChI Key InChIKey=GWYNXNIYWXAMRO-UHFFFAOYSA-N

Data  1 KI  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50617055   

TargetMelanocortin receptor 4(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50617055(CHEMBL5437236)Copy SMILESCopy InChI

Affinity DataKi:  62nMAssay Description:Antagonist activity at human MC4R in CHO cells measured for 24 hrs in presence of alpha-MSHMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/13/2024
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50617055(CHEMBL5437236)Copy SMILESCopy InChI

Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of hERG expressed in CHO cells stably at -80 mV holding potential by automated patch clamp methodMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/13/2024
Entry Details
Copy BDB DOIPubMed
Copy reaction URL