BDBM50617196 CHEMBL5427309

SMILES Cn1c(C(=O)NC2(CC2)c2ccc(cc2)C(O)=O)c(Nc2cccc(c2)C(F)(F)F)c2ccccc12

InChI Key InChIKey=XHFKRGILKWWXLR-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50617196   

TargetProstaglandin E2 receptor EP4 subtype(Human)
Arromax Pharmatech Co.

Curated by ChEMBL
LigandPNGBDBM50617196(CHEMBL5427309)
Affinity DataIC50: 47nMAssay Description:Antagonist activity at human EP4 receptor overexpressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP formation preincubated for 15 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Arromax Pharmatech Co.

Curated by ChEMBL
LigandPNGBDBM50617196(CHEMBL5427309)
Affinity DataKi:  144nMAssay Description:Displacement of [3H]-PGE2 from human EP4 receptor membrane measured after 2 hrs by Microscint-O scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Arromax Pharmatech Co.

Curated by ChEMBL
LigandPNGBDBM50617196(CHEMBL5427309)
Affinity DataKi: >6.40E+3nMAssay Description:Displacement of [3H]-PGE2 from EP3 receptor membrane (unknown origin) measured after 2 hrs by Microscint-O scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
Arromax Pharmatech Co.

Curated by ChEMBL
LigandPNGBDBM50617196(CHEMBL5427309)
Affinity DataKi: >8.80E+3nMAssay Description:Displacement of [3H]-PGE2 from EP2 receptor membrane (unknown origin) measured after 2 hrs by Microscint-O scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Arromax Pharmatech Co.

Curated by ChEMBL
LigandPNGBDBM50617196(CHEMBL5427309)
Affinity DataKi: >9.60E+3nMAssay Description:Displacement of [3H]-PGE2 from EP1 receptor membrane (unknown origin) measured after 2 hrs by Microscint-O scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed