BDBM50617200 CHEMBL5418164

SMILES C[C@H](NC(=O)c1c(Nc2cccc(c2)C(F)(F)F)c2ccccc2n1C)c1ccc(cc1)C(O)=O

InChI Key InChIKey=BBJLZNHEYIHTCB-UHFFFAOYSA-N

Data  4 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50617200   

TargetProstaglandin E2 receptor EP4 subtype(Human)
Arromax Pharmatech Co.

Curated by ChEMBL
LigandPNGBDBM50617200(CHEMBL5418164)
Affinity DataIC50: 4.30nMAssay Description:Antagonist activity at human EP4 receptor overexpressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP formation preincubated for 15 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Arromax Pharmatech Co.

Curated by ChEMBL
LigandPNGBDBM50617200(CHEMBL5418164)
Affinity DataKi:  66nMAssay Description:Displacement of [3H]-PGE2 from human EP4 receptor membrane measured after 2 hrs by Microscint-O scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Arromax Pharmatech Co.

Curated by ChEMBL
LigandPNGBDBM50617200(CHEMBL5418164)
Affinity DataKi: >6.40E+3nMAssay Description:Displacement of [3H]-PGE2 from EP3 receptor membrane (unknown origin) measured after 2 hrs by Microscint-O scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
Arromax Pharmatech Co.

Curated by ChEMBL
LigandPNGBDBM50617200(CHEMBL5418164)
Affinity DataKi: >8.80E+3nMAssay Description:Displacement of [3H]-PGE2 from EP2 receptor membrane (unknown origin) measured after 2 hrs by Microscint-O scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Arromax Pharmatech Co.

Curated by ChEMBL
LigandPNGBDBM50617200(CHEMBL5418164)
Affinity DataKi: >9.60E+3nMAssay Description:Displacement of [3H]-PGE2 from EP1 receptor membrane (unknown origin) measured after 2 hrs by Microscint-O scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
Arromax Pharmatech Co.

Curated by ChEMBL
LigandPNGBDBM50617200(CHEMBL5418164)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at EP2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Arromax Pharmatech Co.

Curated by ChEMBL
LigandPNGBDBM50617200(CHEMBL5418164)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at EP1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Arromax Pharmatech Co.

Curated by ChEMBL
LigandPNGBDBM50617200(CHEMBL5418164)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at EP3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Arromax Pharmatech Co.

Curated by ChEMBL
LigandPNGBDBM50617200(CHEMBL5418164)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of hERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed