BDBM50617256 CHEMBL5415251

SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1cccc(c1)-c1csc(NC(C)=O)n1

InChI Key InChIKey=LBSMEKVVMYSTIH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50617256   

TargetEndoplasmic reticulum chaperone BiP(Human)
The First Affiliated Hospital of Henan University

Curated by ChEMBL
LigandPNGBDBM50617256(CHEMBL5415251)
Affinity DataKd:  2.50E+4nMAssay Description:Binding affinity to GRP78 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEndoplasmic reticulum chaperone BiP(Human)
The First Affiliated Hospital of Henan University

Curated by ChEMBL
LigandPNGBDBM50617256(CHEMBL5415251)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of HspA5 (unknown origin)-dependent IRE1 monomer assessed as increase in IRE1 level measured for 1 hr in presence of ATP/J domain of ERdj4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed