BDBM50617371 CHEMBL5419623

SMILES [O-][N+](=O)c1ccc(NCC(=O)N2CCN(CC2)S(=O)(=O)c2ccc(NC(=S)NCc3cccnc3)cc2)c2nonc12

InChI Key InChIKey=DJFDWKLQGDBMEZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50617371   

TargetNicotinamide phosphoribosyltransferase(Human)
Second Military Medical University (Naval Medical University)

Curated by ChEMBL
LigandPNGBDBM50617371(CHEMBL5419623)
Affinity DataIC50: 15nMAssay Description:Inhibition of NAMPT (unknown origin) using PRPP as substrates incubated in presence of ATP by fluorimetric plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Second Military Medical University (Naval Medical University)

Curated by ChEMBL
LigandPNGBDBM50617371(CHEMBL5419623)
Affinity DataIC50: 480nMAssay Description:Inhibition of NAMPT in human A2780 cells measured at 48 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Second Military Medical University (Naval Medical University)

Curated by ChEMBL
LigandPNGBDBM50617371(CHEMBL5419623)
Affinity DataIC50: 770nMAssay Description:Inhibition of NAMPT in human A2780 cells measured at 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Second Military Medical University (Naval Medical University)

Curated by ChEMBL
LigandPNGBDBM50617371(CHEMBL5419623)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NAMPT in human A2780 cells measured at 6 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed