BDBM50617708 CHEMBL5394928::US20250353857, Compound TIA02-132

SMILES CN(Cc1cccc(F)c1)c1ncnc2[nH]c(nc12)-c1ccc(CO)cc1

InChI Key InChIKey=VOMLWCOJPBAYCX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50617708   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617708BDBM50617708(CHEMBL5394928 | US20250353857, Compound TIA02-132)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617708BDBM50617708(CHEMBL5394928 | US20250353857, Compound TIA02-132)
Affinity DataIC50: 3.5nMAssay Description:The compounds were supplied in a 10 mM DMSO solution, and enzymatic CSF1R inhibition potency was determined by Invitrogen (TermoFisher) using their Z...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2026
Entry Details