BDBM50617711 CHEMBL5399857::US20250353857, Compound TIA03-014

SMILES COc1cccc(CN(C)c2ncnc3[nH]c(nc23)-c2ccc(CO)cc2)c1

InChI Key InChIKey=CGGZSMCAABSIGY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50617711   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617711BDBM50617711(CHEMBL5399857 | US20250353857, Compound TIA03-014)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617711BDBM50617711(CHEMBL5399857 | US20250353857, Compound TIA03-014)
Affinity DataIC50: 2.70nMAssay Description:The compounds were supplied in a 10 mM DMSO solution, and enzymatic CSF1R inhibition potency was determined by Invitrogen (TermoFisher) using their Z...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2026
Entry Details