BDBM50617713 CHEMBL5414671::US20250353857, Compound TIA03-080

SMILES COc1ccc(CN(C)c2ncnc3[nH]c(nc23)-c2ccc(CO)cc2)cc1OC

InChI Key InChIKey=ASHCEINTWXMABT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50617713   

LigandChemical structure of BindingDB Monomer ID 50617713BDBM50617713(CHEMBL5414671 | US20250353857, Compound TIA03-080)
Affinity DataIC50: 5.70nMAssay Description:The compounds were supplied in a 10 mM DMSO solution, and enzymatic CSF1R inhibition potency was determined by Invitrogen (TermoFisher) using their Z...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 50617713BDBM50617713(CHEMBL5414671 | US20250353857, Compound TIA03-080)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed