BDBM50617730 CHEMBL5405639

SMILES CN(Cc1ccccc1)c1ncnc2[nH]c(cc12)-c1ccccc1

InChI Key InChIKey=XDCJXTNEYNEENX-UHFFFAOYSA-N

Data  3 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50617730   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (NTNU)

Curated by ChEMBL
LigandPNGBDBM50617730(CHEMBL5405639)
Affinity DataIC50: 15nMAssay Description:Inhibition of CSF1R (530 to 910 residues) (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (NTNU)

Curated by ChEMBL
LigandPNGBDBM50617730(CHEMBL5405639)
Affinity DataIC50: 15nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (NTNU)

Curated by ChEMBL
LigandPNGBDBM50617730(CHEMBL5405639)
Affinity DataIC50: 15nMAssay Description:Inhibition of CSF1R (unknown origin) using EEEIYGEFE as substrate in presence of ATP by Z-LYTE based FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (NTNU)

Curated by ChEMBL
LigandPNGBDBM50617730(CHEMBL5405639)
Affinity DataIC50: 20nMAssay Description:Inhibition of CSF1R (unknown origin) using ultra ULight GT peptide as substrate incubated for 1 hr in presence of 25 uM of ATP by LANCE Ultra based T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (NTNU)

Curated by ChEMBL
LigandPNGBDBM50617730(CHEMBL5405639)
Affinity DataKd:  52nMAssay Description:Binding affinity to autoinhibited CSF1R (538 to 939) (unknown origin) expressed in Escherichia coli BL21 strain assessed as dissociation constant inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Norwegian University of Science and Technology (NTNU)

Curated by ChEMBL
LigandPNGBDBM50617730(CHEMBL5405639)
Affinity DataIC50: 100nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (NTNU)

Curated by ChEMBL
LigandPNGBDBM50617730(CHEMBL5405639)
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to non-autoinhibited CSF1R (564 to 939) (unknown origin) expressed in Escherichia coli BL21 strain assessed as dissociation constant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed