BDBM50617731 CHEMBL5431583::US20250353857, Compound KUL01-123
SMILES CN(Cc1ccccc1)c1ncnc2[nH]c(cc12)-c1ccc(CO)cc1
InChI Key InChIKey=KVBFMJDTLAIVSN-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50617731
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (NTNU)
Curated by ChEMBL
Norwegian University of Science and Technology (NTNU)
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of CSF1R (530 to 910 residues) (unknown origin)More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (NTNU)
Curated by ChEMBL
Norwegian University of Science and Technology (NTNU)
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of CSF1R (530 to 910 residues) (unknown origin)More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (NTNU)
Curated by ChEMBL
Norwegian University of Science and Technology (NTNU)
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:The compounds were supplied in a 10 mM DMSO solution, and enzymatic CSF1R inhibition potency was determined by Invitrogen (TermoFisher) using their Z...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (NTNU)
Curated by ChEMBL
Norwegian University of Science and Technology (NTNU)
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:The compounds were supplied in a 10 mM DMSO solution, and enzymatic CSF1R inhibition potency was determined by Invitrogen (TermoFisher) using their Z...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (NTNU)
Curated by ChEMBL
Norwegian University of Science and Technology (NTNU)
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Human)
Norwegian University of Science and Technology (NTNU)
Curated by ChEMBL
Norwegian University of Science and Technology (NTNU)
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Human)
Norwegian University of Science and Technology (NTNU)
Curated by ChEMBL
Norwegian University of Science and Technology (NTNU)
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Human)
Norwegian University of Science and Technology (NTNU)
Curated by ChEMBL
Norwegian University of Science and Technology (NTNU)
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of EGFR (unknown origin) in presence of ATPMore data for this Ligand-Target Pair